July 17, 2025
In 2022, we published a seminal paper titled "Payload distribution and capacity of mRNA lipid nanoparticles", in which we used cylindrical illumination confocal spectroscopy (CICS) to characterize mRNA lipid nanoparticles (LNPs) and became the first to report single-nanoparticle mRNA loading level and empty LNP ratios. The paper filled a very important technical gap in precisely profiling nanomedicine for quality control and R&D purposes, and clearly demonstrates commercialization opportunities in a broad field of nanomedicine. Since its publication, we have collaborated with several leading companies in the gene and cell therapy and vaccine fields, with CICS implemented and driving new discoveries.
Now, we are pleased to announce that CICS Analytics Corporation was founded. Dr. Sixuan Li, the inventor of the CICS platform, will continue to lead the company towards fully realizing the value of the technology. Congratulations to the entire team!